Symbol
Name
ID

Kiss1r
KISS1 receptor
MGI:2148793

Phenotype annotations related to endocrine/exocrine glands

Darker colors indicate more annotations

Human Phenotypes	Decreased circulating follicle stimulating hormone concentration	Elevated circulating follicle stimulating hormone level	Decreased circulating luteinizing hormone level	Elevated circulating luteinizing hormone level	Hypothyroidism	Absence of pubertal development	Isosexual precocious puberty	Hypogonadotropic hypogonadism	Male hypogonadism
Disease(s) Associated with KISS1R		Elevated circulating follicle stimulating hormone level	Decreased circulating luteinizing hormone level	Elevated circulating luteinizing hormone level	Hypothyroidism	Absence of pubertal development	Isosexual precocious puberty	Hypogonadotropic hypogonadism	Male hypogonadism
central precocious puberty 1
hypogonadism
hypogonadotropic hypogonadism 8 with or without anosmia

Mouse Phenotypes

retention of the adrenal gland x-zone

abnormal adrenal cortex morphology

decreased adrenal gland weight

increased thymus weight

abnormal branching of the mammary ductal tree

mammary gland hypoplasia

absent male preputial gland

small male preputial gland

decreased prostate gland weight

small prostate gland

absent prostate gland

abnormal seminal vesicle morphology

decreased seminal vesicle weight

small seminal vesicle

seminal vesicle hypoplasia

absent seminal vesicle

abnormal ovary morphology

absent corpus luteum

absent mature ovarian follicles

absent ovarian follicles

increased atretic ovarian follicle number

decreased ovary weight

small ovary

absent ovary

abnormal testis morphology

small seminiferous tubules

seminiferous tubule degeneration

decreased Leydig cell number

decreased testis weight

small testis

absent testes

Availability

Mouse Genotype

Kiss1r^Gt1Stei/Kiss1r^Gt1Stei

Kiss1r^{tm1.1(KOMP)Vlcg}/Kiss1r^{tm1.1(KOMP)Vlcg}

Kiss1r^tm1.1Lex/Kiss1r^tm1.1Lex

Kiss1r^tm1Coll/Kiss1r^tm1Coll

Kiss1r^tm1Gstn/Kiss1r^tm1Gstn

Kiss1r^tm1Rla/Kiss1r^tm1Rla

Kiss1r^tm1.1Aeh/Kiss1r^tm1.1Aeh
Tg(Gnrh1-cre)1Dlc/0 (conditional)

Kiss1r^tm1.1Hjn/Kiss1r^tm1.1Hjn
Tg(Gnrh1-cre)35Awo/0 (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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